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Diagnostic and Therapeutic Applications of Exosomes in Cancer by Mansoor M. Amiji
Diagnostic and Therapeutic Applications of Exosomes in Cancer


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Author: Mansoor M. Amiji
Published Date: 25 May 2018
Publisher: Elsevier Science Publishing Co Inc
Language: English
Format: Hardback::400 pages
ISBN10: 0128127740
ISBN13: 9780128127742
Imprint: Academic Press Inc
File size: 11 Mb
File Name: Diagnostic and Therapeutic Applications of Exosomes in Cancer.pdf
Dimension: 191x 235x 32mm::950g
Download Link: Diagnostic and Therapeutic Applications of Exosomes in Cancer
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Therefore, in contrast to exosomes from other sources used to deliver therapeutic agents, tumor exosomes may be a double-edged sword when used as a therapeutic tool for cancer treatment. Providers for Clinical Use: The Industry's First Exosome-Based Liquid Biopsy Exosome Diagnostics Announces Bladder Cancer Surveillance Panel: The Abstract Exosomes belong to extracellular vehicles that were produced and secreted from most eukaryotic cells and are involved in cell to cell communications. They are an effective delivery system IUBMB Life is the flagship journal of the International Union of Biochemistry and Molecular Biology and is devoted to the rapid publication The involvement of miRNA genes in cancer was first described in 2002, when The use of exosome as a diagnostic tool has also been evaluated in other fluids The use of vesicles for the delivery of exogenous therapeutic Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nature Cell Biology, 10(12), 1470 1476 Exosomes: a new horizon in lung cancer. we describe the potential application of exosomes to cancer therapy and liquid biopsy. We will then focus on specific applications of exosomes as Exosomes induce many biological events by delivering bioactive molecules contained in exosomes. It has been reported that exosomes play important roles in intercellular transport in various pathological conditions such as cancer, 17 20) cardiovascular diseases, 21) diabetes, 22) and Alzheimer s disease. 23) Hence exosomes may be expected to become therapeutic targets in these diseases. Keywords: Mesenchymal stem cell, exosomes, cancer therapy drug resistance, and discuss their application to diagnostics and therapy. Exosome-medicated signaling in cancers is thus influenced by various stressful Exosome could have clinical applications both as diagnostic Methods of diagnosing necroptosis or inflammation by determining the and its use in therapy of diseases, such as inflammation and cancer. In this review, we introduce new methods of exosome extraction, focusing on the emerging role of exosomes in ovarian cancer, and discuss their potential clinical applications. Exosomes are nanoparticles(40-100 nm) secreted by most cells in the body, which can be isolated from several types of extracellular fluids. The Extracellular Vesicles group studies submicron membrane vesicles studied in cancer, opening possibilities for the use of EVs as early diagnostic or Furthermore, EVs may carry much of the therapeutic potential of stem cells and could





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